By its performance parameters oxymetholone is most similar to methandienone. As with methandienone, it provokes not only active muscle bulking, but also a significant increase in power performance. However, a large part of the gained weight is because of water retention in the body, which can lead to high blood pressure on cycle.

Thanks to its ability to influence the level of hemoglobin and to increase the blood volume in the body, oxymetholone may cause an extremely strong pumping effect by athletes, which consequently complicates the training process, because muscles get sore almost immediately after the first heavy set.